Aug 18, 2021
Use it or Lose it
We’ve all heard the phrase ‘use it or lose it’. Here’s some evidence that supports that this may be true in the development of Alzheimer’s disease.
A common comment by patients to the memory clinic, is that their memory is impaired because they haven’t been doing anything or talking to anyone. Lockdown in particular saw some people’s memory declined faster than it may have done. Why did the pandemic lead to a worsening of their memories? Read more
Apr 8, 2021
Gut dysbiosis and Alzheimer’s disease
One of the possible mechanisms contributing to the development of Alzheimer’s disease is gut dysbiosis. Gut dysbiosis is where the intestinal flora or bacteria living in the large intestines are unbalanced. Amino acids produced by less beneficial bacteria can trigger an inflammatory response leading to neuroinflammation.
New drug therapies have been developed and are being trialed that remodel the microbiome. Reducing these amino acids may reduce the infiltration of immune cells to the brain, and in turn reduce neuroinflammation. Read more